脱细胞基质材料生物补片在青少年(6～18岁)患者腹股沟疝修补术中应用的研究

Inguinal hernia repair with acellular tissue matrix for pediatric patients aged 6 to 18 years

目的探讨脱细胞组织基质材料生物补片在青少年(6～18岁)腹股沟疝患者治疗中应用的价值,为这一特定人群腹股沟疝修补手术的治疗提供新的思路与材料。方法选择2009年7月至2009年12月间共30例符合入选标准的青少年腹股沟疝患者,使用广东冠昊公司生产的脱细胞基质材料生物补片行腹股沟疝Lichtenstein平片无张力修补术,记录患者手术前后的临床参数,观察并分析术后并发症及复发情况。结果术后随访观察12～18个月,未出现生物材料过敏病例,未出现伤口感染,术后阴囊积液3例,无慢性疼痛和局部异物感,无复发病例。结论在青少年腹股沟疝患者的治疗中应用脱细胞基质材料的生物补片行平片无张力疝修补手术,效果良好,不增加术后相关并发症,理论上可更好地预防复发,具有一定应用前景。

Objective To evaluate the safety and efficacy of hernioplasty using acellular tissue matrix to repair inguinal hernia of pediatric patients aged 6 to 18 years,and try to provide a potential treatment to this specific group.Methods Thirty eligible patients aged 6 to 18 years with inguinal hernia were enrolled in the study from July to December in 2009,the patients managed with acellular tissue matrix（Grandhope Biotech Co.,Ltd.）.Preoperative and postoperative parameters such as clinical informations of patients,postoperative complications and recurrence rate were recorded and analyzed.Results There were no post-operative incisional infection,and no material hypersensitivity occurred among patients during the followed-up time from 12 to 18 months,3 patients suffered scrotal hydrocele whereas there were no recurrence,chronic pain and local foreign body sensation.Conclusions Lichtenstein repair for pediatric patients aged 6 to 18 years with acellular tissue matrix has good results and with limited postoperative complications,and could be applied in the clinical practice to prevent the recrudescence.