呼吸内科病房医院感染病原菌的鉴定及耐药性分析

Respiratory Nnosocomial Infections Identification of Pathogens and Drug Resistance

目的了解我院呼吸内科病房医院感染病原菌的鉴定及耐药性情况,为呼吸科医生正确使用抗生素提供指导依据。方法对我院呼吸内科2006年1月1日～2009年12月31日所分离鉴定的病原菌株及其耐药性进行总结分析。结果 1000株病原菌中G^-杆菌占51.7%,G^+球菌占28.7%,真菌占19.6%。G^-杆菌以铜绿假单胞菌、大肠埃希菌为主,分别占G★杆菌的17.2%和14.5%,其次为肺炎克雷伯菌(占7.6%)、肠杆菌(占5.2%)。G^+球菌以金黄色葡萄球菌为主(占17.0%)。真菌以白色假丝酵母菌为主,占14.2%。结论呼吸内科病人感染细菌以阴性杆菌为主,呈现细菌种类多、耐药率高的特点,选择抗生素时应依据患者的细菌和药敏结果,避免耐药菌的产生成为医院管理和感染控制的重要内容。在临床实践中要及时进行流行病学监测,降低抗菌药物用药频度,减少耐药性的发生,指导临床合理用药。

Objective To understand respiratory nosocomial infections and resistant pathogens in the identification of conditions for respiratory physicians to provide guidance based on the proper use of antibiotics. Methods From Respiratory Medicine January 1,2006 Dec. 31,2009 by isolated strains of pathogenic bacteria and drug resistance were analyzed. Results 1000 G- bacilli bacteria in 51.7%,G^ cocci accounted for 28.7%,19.6% fungi. G bacteria Pseudomonas aeruginosa,Escherichia coli,G- bacilli accounted for 17.2% and 14.5%,followed by Klebsiella pneumoniae（7.6%）,Enterobacter （5.2%）. G＋ cocci,Staphylococcus aureus （17.0%）. Candida albicans fungi,accounting for 14.2%. Conclusion Respiratory bacterial infection in medical patients with negative bacillus,showing various types of bacteria,the characteristics of high resistance,choice of antibiotics should be based on the results of patients and antimicrobial sus- ceptibility of bacteria to avoid the generation become resistant hospital management and infection control important.In chnical practice, epidemiological surveillance to promptly reduce the frequency of antimicrobial drugs in reducing the incidence of drug resistance,clinical therapy.