瞬时波强度技术评价扩张型心肌病病人左心室收缩功能的研究

The Wave Intensity for Evaluation of Left Ventricular Function of Dilated Cardiomyopathy

目的探讨瞬时波强度(WI)技术评价扩张型心肌病(DCM)病人左心室收缩功能的应用价值。方法应用WI技术对25例扩张型心肌病病人及25名正常人的右侧颈总动脉进行检测,获得WI各参数,将两组参数进行比较。结果 DCM组左室射血分数(LVEF)和左室短轴缩短率(FS)均显著低于对照组(P<0.01),左室舒张末期内径(LVEDd)和左室收缩末期内径(LVESd)均显著大于对照组(P<0.01);与对照组比较,DCM组收缩早期峰值(W1)显著降低(P<0.01);DCM组心电图R波到W1的时间间隔(R-1st)显著延长(P<0.05),W1至W2的时间间隔(1st-2nd)显著减低(P<0.05),DCM组W1与LVEF呈显著正相关(r=0.71,P<0.05)。结论 WI技术可评价扩张型心肌病病人的左心室收缩功能,为临床正确的诊断疾病及判断病情提供可靠的信息。

Objective To investigate the wave intensity（WI） technique to assess the systolic function of left ventricle in patients（pts） with dilated cardiomyopathy（DCM）.Methods Twenty-five pts with DCM and 25 healthy subjects were examined with high frequency ultrasonography.Right common carotid artery was targeted for ultrasonic imaging to obtain WI parameters.Results The ejection fraction（LVEF）and fractional shortening（FS）in DCM group were significantly lower compared with that in control group（P0.01）.The left ventricular end-diastolic diameter（LVEDd）and left ventricular end-systolic diameter（LVESd）in DCM group were significantly higher compared with that in control group（P0.01）.The W1 and time（1st-2nd） in DCM group were lower compared with that in control group（P0.05）,while R-1st was higher（P0.05）.The W1 was closely related to LVEF in DCM group（r=0.71,P0.05）.Conclusion The WI technique could evaluate the left ventricular systolic function for pts with DCM.