以MAP为洗液的洗涤红细胞可行性研究

FEASIBILITY STUDY OF MAP WASHED RED BLOOD CELLS

目的探讨用MAP洗涤悬浮红细胞制备的洗涤红细胞的质量,观察关键指标的变化。方法对比MAP洗涤红细胞和盐水洗涤红细胞的红细胞回收率、白细胞清除率、血浆蛋白清除率、K+浓度及血红蛋白游离率的差异。结果盐水组和MAP组红细胞回收率、白细胞清除率、血浆蛋白清除率、K+浓度及血红蛋白游离率比较无显著性差异(p>0.05)。结论 MAP制备的洗涤红细胞各项质量指标符合国家标准,能应用于临床。

Objective To investigate quality of washed red blood cell prepared by using MAP erythrocyte preserve fluid. Methods Hemoglobin concentration, platelet count, white blood cell count, K ＋ concentration and count of plasma proteins supernatant fluid were measured before and after red blood cells were washed by MAP or nor- mal saline. Results There is no significantly statistical difference （p 〉 0. 05 ） between the two groups on red blood cell recovery rates, white blood cells removal rates were, platelets removal rates, plasma proteins removal rates, K ＋ re- moval rates and free hemoglobin rates. Conclusion Our data indicates that MAP washed red blood ceils have reliable qualifies and are more safe for transfusion.