嗜酸性粒细胞肺炎1例并文献复习

A case of eosinophilic pneumonia and review of related literature

目的总结1例诊断和治疗嗜酸性粒细胞肺炎1例的临床过程。方法对本院成功治疗1例嗜酸性粒细胞肺炎病例的临床资料进行分析,并文献复习。结果此例有顽固性喘息、血嗜酸性粒细胞增高、右下肺外周浸润影像学改变,患者给予糖皮质激素,辅以抗生素,止咳化痰等对症支持治疗,病情迅速好转,嗜酸性粒细胞恢复正常,治疗四天后胸部CT右侧结节影几近完全吸收,住院12 d后好转出院。结论嗜酸性粒细胞肺炎有着特有的典型症状,体征,影像学改变,容易被误诊,给予糖皮质激素维持治疗后可显著改善症状并控制病情的发展,改善预后。

Objective To summarize the diagnosis and treatment of a case of eosinophilic pneumonia in the clinical process,providing clinical experience,for avoiding and reducing misdiagnosis.Methods To analyse a eosinophilic pneumonia which treated successfully in our hospital,and summarize the clinical features,diagnosis and treatment progress of the case.Furtherly review the related literature.Results The patient had experienced with refractory wheeze,eosinophilia,and infiltration in peripheral right lower lung in CT.Treated with corticosteroid-maintained therapy,supplemented with antibiotics to prevent infection,the symptoms were rapidly improved,and the eosinophils returned to normal.After twelve days＇ treatment,the nodules near the right side of the chest were completely absorbed.Conclusions Eosinophilic pneumonia is characterized with typical symptoms,signs and chest imaging,which is clinically diagnosed mostly and easily misdiagnosed,glucocorticoid-maintained therapy can significantly improve symptoms and control the progresses.