振动反应成像在慢性阻塞性肺疾病及支气管哮喘中的应用研究

Exploration of Vibration Response Imaging system in diagnosing the copd and asthma

目的研究慢性阻塞性肺疾病(COPD)及支气管哮喘振动反应(VR I)图像,了解VR I在COPD及支气管哮喘患者病情监测中的作用。方法 87例因COPD入院患者为第1组,同期64例哮喘患者为第2组,护工22例为健康组。3组均行肺功能及VR I等检查,COPD组采集2次(入院及出院时),分析3组患者VR I变量特点。结果 COPD组及哮喘组在振动能量曲线、EVP振幅、MEF面积等方面差异均有统计学意义。两组与健康组VR I各变量均有显著差异。COPD组2次肺功能无差异,VR I各变量明显改善,6例临床病情变化前VR I已变化。结论健康人、COPD患者及支气管哮喘VR I图像有明显差异,VR I定时监测能提前COPD干预治疗。

Objective Vibration response imaging diagnosis system（VRI）was used to collect the lung image from normal people,COPD and Asthmatic patients.And to evaluate the characteristics of vibration response image in COPD and asthma.Methods The COPD group had 87 patients and the control group had 64 asthmatic patients,which admitted to hospital on the same time.the normal people were 22 case.after taking lung function test and VRI exam analyzed the three group′s VRI parameter by blind.The COPD repeat twice（when admited and when out of the hospital）.The vibration image were analyzed.Results Vibration energy graphy in expiration phase in COPD and asthma is low and flat,vibration dimension of EVP,inequality of MEF area of left and right area is higher in COPD than in asthma（P0.05）.the inconsistency in vibration response image development,inconsistency of EVP,the ratio of wet rales and deficiency rale of MEF,average QLD in 12 seconds period and periodical average QLD during expiration phase in left middle area in Asthma is higher than that in COPD（P0.05）.six case of the COPD are found：before the clinic symptoms come out,the VRI image change.Conclusion vibration response image in COPD and in Asthma is significantly different,it is useful in differential diagnosis between COPD and Asthma.it can be predict or monitor the COPD′S clinic manifestetions progression.