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蛋白酶与抗蛋白酶失衡在COPD中的研究进展 被引量:10

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摘要 COPD以气道、肺实质和肺血管慢性炎症性病变为特征。大多数研究证实,COPD的发病机制除了炎症及氧化应激外,另外还有蛋白酶与抗蛋白酶失衡。很早以前就有学术假说认为COPD组织损伤是由于由中性粒细胞和巨噬细胞产生的蛋白酶与从血浆渗出的抗蛋白酶失衡引起的。
出处 《临床肺科杂志》 2011年第3期437-440,共4页 Journal of Clinical Pulmonary Medicine
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