椎动脉病变节段与颈性眩晕发病的关系研究

Research on the relation between pathogenic segment of the vertebral artery and cervical vertigo

目的:探讨椎动脉病变节段与颈性眩晕发病的关系。方法:对纳入研究的500例患者进行详细的体格检查、X线摄片及TCD检查,统计分析患者年龄与性别、病变节段与性别、病变节段与致病因素、病变节段与年龄、致病因素与年龄之间的关系。结果:①各年龄段患者性别构成比的差异有统计学意义(2χ=15.242,P=0.001),30岁以上患者中女性多于男性。②各病变节段性别构成比的差异无统计学意义(2χ=5.501,P=0.139),第3段的患者比例明显高于其他节段。③各病变节段致病因素的构成比有差异(2χ=279.733,P=0.000),病变节段与致病因素间有关联性(r=0.435)。④各病变节段年龄构成比的差异有统计学意义(2χ=69.239,P=0.000)。经2χ分割(校正α=0.008),第3段与第1段、第2段、第4段的差异均有统计学意义(2χ=10.257,P=0.006;2χ=44.890,P=0.000;2χ=43.919,P=0.000),其余各节段间年龄构成比的差异均无统计学意义(P=0.083)。⑤不同年龄段患者致病因素构成比的差异有统计学意义(2χ=74.456,P=0.000),发病年龄与致病因素有关联性(r=0.265)。结论:椎动脉病变节段与颈性眩晕的发病具有关联性。

Objective：To explore the relation between pathogenic segment of the vertebral artery and cervical vertigo.Methods：500 patients undergone physical examination,X-ray examination and TCD examination.The patients＇ age,sexuality,pathogenic segment and etiological factors were documented and the correlation of these factors were analyzed.Results：①The difference of sex constituent ratio was significant between different age stage（χ2=15.242,P=0.001）.More women than men were found in patients older than 30 years.②The difference of sex constituent ratio between different pathogenic segments of the vertebral artery was not statistically significant（χ2=5.501,P=0.139）.The highest incidence was found in the third segment of the vertebral artery.③Constituent ratio of etiological factors was significantly different between different pathogenic segments（χ2=279.733,P=0.000）and relevance presented between pathogenic segment and etiological factor（r=0.435）.④There was statistical difference of age constituent ratio between pathogenic segments（χ2=69.239,P=0.000）.There was statistical difference of age constituent ratio between the third segment and other segment（χ2=10.257,P=0.006;χ2=44.890,P=0.000;χ2=43.919,P=0.000） and the differences of age constituent ratio between the first,second and fourth segment were not statistically significant（P=0.083）.⑤There was statistical difference of constituent ratio of etiological factors between different age stage（χ2=74.456,P=0.000）and relevance appeared between age of onset and etiological factors（r=0.265）.Conclusion：Pathogenic segment of the vertebral artery has close relation with cervical vertigo.