结直肠手术前3种机械肠道准备药物的临床效果比较

Comparison on the Clinical Efficacies of Three Mechanical Bowel Preparation for Colorectal Operation

为探讨口服磷酸钠溶液与复方聚乙二醇电解质散剂行肠道准备的安全性和实用性，将60例结直肠手术患者随机分为3组，分别采用口服磷酸钠溶液（SP组）、复方聚乙二醇电解质散剂（PEG组）和甘露醇组行手术前的肠道准备，观察每组肠道准备前后的血清学指标，肠道清洁程度，患者对药物的耐受性以及手术前后患者的一般情况。3组肠道准备方法在患者的血清学指标，肠道清洁程度等方面无显著性差异，但甘露醇组的腹泻次数明显多于SP组及PEG组，且耐受性较低。结果表明，口服磷酸钠溶液及复方聚乙二醇电解质散剂肠道准备法是安全、可靠的，具有较好的实用价值。

In order to probe into the safety and feasibility of bowel preparation with orally administering sodium phosphate（SP） solution and compound polyethylene glycol（PEG） electrolyte powder authors divided 60 patients to be received colorectal operation into three groups,who received SP,PEG and mannitol respectively（named as A,B and C group） for intestinal preparation before operation, then the serology indexes, clean extents of intestinal tract and general status of patients before and after the preparation, as well the tolerance of patients to drugs were observed and compared each other. As results,among the 3 preparation in former two method there was not significant difference,but in C group the times of diarrhea of patients were significantly more than that in A, B group,and their tolerance also lower. Results show that the former two preparations are safe,feasible,and has better pratical value.