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Tourette综合征患儿三种肺炎支原体特异性抗体的检测Tourette综合征患儿三种肺炎支原体特异性抗体的检测 被引量：1

Three specific antibodies level of mycoplasma pneumoniae in children with Tourette＇s syndrome
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摘要 目的 探讨肺炎支原体（MP）感染与Tourette综合征（TS）的关系.方法 根据美国耶鲁综合抽动严重程度量表（YCTSS）评分,将4l例TS患儿（TS组）分为轻度组和中重度组,以同期健康儿童60例作为对照组,采用酶联免疫吸附法测定2组血清中MP特异性抗体免疫球蛋白A（MP-IgA）、免疫球蛋白G（MP-IgG）、免疫球蛋白M（MP-IgM）的水平;观察TS组与对照组是否存在血清MP-IgA、MP-IgG、MP-IgM的差别.结果 TS组MP-IgA阳性率（24.39%）和MP-IgG阳性率（53.66%）均高于对照组（6.67%,28.33%）,差异均有统计学意义（P均＜0.05）;TS组MP-IgM阳性率与对照组比较,差异无统计学意义（P＞0.05）.结论 MP感染与TS发病可能存在一定的联系. Objective To explore the association between mycoplasma pneumoniae infection and Tourette syndrome. Methods The serum mycoplasma pneumoniae-IgA, -IgG, -IgM in 41 children with Tourette syndrome and 60 healthy children were measured with ELISA method. Results The positive rate of mycoplasma pneumoniae IgA（ 24. 39% ）and IgG（ 53.66% ） in Tourette syndrome group were higher than that of control group（ 6. 67% and 28. 33%）（ P 〈0. 05 ）. The positive rate of mycoplasma pneumoniae-IgM was not different between patient and healthy children. Conclusion Mycoplasma pneumoniae infection may be associated with Tourette syndrome.
作者 张建昭 杨健 李尔珍 吴建新 崔小岱 王立文 王昕 孙春荣
机构地区 首都儿科研究所附属儿童医院神经内科 首都儿科研究所附属儿童医院生化实验室 首都儿科研究所附属儿童医院临床实验室
出处 《中华精神科杂志》 CAS CSCD 北大核心 2011年第1期14-16,共3页 Chinese Journal of Psychiatry
关键词 多动秽语综合征 肺炎 支原体 感染 免疫球蛋白类 Tourette syndrome Pneumonia,mycoplasma Infection Immunoglobulins
分类号 R749.94 [医药卫生—神经病学与精神病学]
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参考文献19

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共引文献1024

同被引文献15

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中华精神科杂志
2011年 第1期

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