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多巴胺D1受体基因与早发性精神分裂症家系的传递不平衡研究 被引量:4

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摘要 为了解多巴胺D1受体(DRD1)与精神分裂症的关系,我们检测了95个早发性精神分裂症核心家系,从分子水平上对两者间的关系进行探讨.
出处 《中华精神科杂志》 CAS CSCD 北大核心 2011年第1期59-59,共1页 Chinese Journal of Psychiatry
基金 国家自然科学基金资助项目(30500181) 上海市自然科学基金资助项目(10ZR1425700)
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参考文献3

  • 1Zhang C,Fang Y,Xie B,et al.No genetic association between dopamine D1 receptor gene and[early onset] schizophrenia.Psychiatry Res,2010,177:350-353.
  • 2Batel P,Houchi H,Daoust M,et al.A haplotype of the DRD1gene is associated with alcohol dependence.Alcohol Clin Exp Res,2008,32:567-572.
  • 3Huang W,Ma JZ,Payne TJ,et al.Significant association of DRD1 with nicotine dependence.Hum Genet,2008,123:133-140.

同被引文献40

  • 1赵爱玲,赵靖平,薛志敏,陈晋东,陈晓岗,刘哲宁,李乐华.多巴胺D_4受体基因与精神分裂症质量性状和数量性状的关联分析[J].中华精神科杂志,2005,38(1):3-6. 被引量:6
  • 2唐迅,李娜,胡永华.应用多因子降维法分析基因-基因交互作用[J].中华流行病学杂志,2006,27(5):437-441. 被引量:30
  • 3Rybakowski JK, Borkowska A, Czerski PM,et al An association study of dopamine receptors polymorphisms and the Wisconsin Card Sorting Test in schizophrenia. J Neural Trans,2005,112 : 1575-1582.
  • 4Coyle JT,Balu D,Benneyworth M,et al. Beyond the dopamine receptor: novel therapeutic targets for treating schizoptlrenia. Dialogues Clin Neurosci ,2010,12:359-382.
  • 5Allen NC, Bagade S, McQueen MB, et al. Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: the SzGene database. Nat Genct,2008,40:827-834.
  • 6Zhang C, Fang YR, Xie B, et al. No genetic association between dopamine DI receptor gene and [ early onset] schizophrenia. Psychiatry Res, 2010,177 : 350 -353.
  • 7Funahashi S. Neuronal mechanisms of executive control by the prefrontal cortex. Neurosci Res,2001,39 : 147-165.
  • 8Zheng Y,Wang X, Gu N, et al. A two-stage linkage analysis of Chinese schizophrenia pedigrees in 10 target chromosomes. Biochem Biophys Res Commun,2006,342:1049-1057.
  • 9Zhang C, Li Z, Shao Y, et al. Association study of tryptophan hydroxy- lase-2 gene in schizophrenia and its clinical features in Chinese Han Population. J Mol Neurosci ,2011.43:406-411.
  • 10Potkin SG, Basile VS,Jin Y, et al. D1 receptor alleles predict PET metabohc correlates of clinical response to clozapine. Mol Psychiatry, 2003,8 : 109-113.

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