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γ珠蛋白基因的表达调控研究进展 被引量:1

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摘要 γ珠蛋白属于β类珠蛋白,主要在出生前后表达,与仅珠蛋白相结合形成HbF。人类在出生前后经历一个胎儿到成人的珠蛋白开关转换机制,即完成一个由γ→β的表达转换。研究表明,重新激活1珠蛋白基因的表达,使其与过剩的d珠蛋白相结合可以有效地减轻因β珠蛋白合成减少所致的β地中海贫血、
作者 李冉 吴新忠
出处 《实用医学杂志》 CAS 北大核心 2011年第4期694-696,共3页 The Journal of Practical Medicine
基金 广东省医学科研基金资助项目(编号:A2010215)
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参考文献18

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