低分子肝素治疗急性脑梗死的临床研究

The Clinical Observation of Low Molecular Weight Heparin in the Treatment of 56 Cases with Acute Cerebral Infarction

目的评价低分子肝素在急性脑梗死治疗中的疗效及安全性。方法选取2005年2月至2008年4月就诊于我院符合条件的急性脑梗死患者112例,随机分为治疗组与对照组,各56例,治疗组给予基础治疗+低分子肝素治疗,对照组给予基础治疗。结果治疗组总有效率为89.3%,对照组总有效率为75.0%,χ2=3.896,P<0.05,两组间差异有统计学意义。治疗组PT、APTT、BT及CT在治疗前后均无统计学意义(P>0.05)。结论低分子肝素治疗急性脑梗死有效,且较为安全。

Objective To evaluate the efficacy and safety of the low molecular weight heparin in the treatment of acute cerebral infarction.Methods 2005-2~2008-4 112 eligible patients withacute cerebral infarction were randomly divided into treatment group and control group, treatment group was treated with low molecular weight heparin and basic treatment,and control group received basic treatment.Results The total effective rate in treatment group was 89.3%,and the total effective rate of Control group was 75.0%,χ2=3.896,P0.05,and there were significant differences between the two groups.PT, APTT, BT and CT in treatment group before and after treatment were not statistically significant（P0.05）.Conclusion The low molecular weight heparin for the treatment of acute cerebral infarction was effective and relatively safe.