特发性黄斑前膜术后中医证型及黄斑区视网膜厚度的临床分析

Relationship of TCM Syndrome Patterns with Retinal Thickness of Patients after Idiopathic Macular Epiretinal Membrane Surgery

目的:探讨特发性黄斑前膜术后中医辨证分型与黄斑区视网膜厚度的关系。方法:将75例患者根据辨证分为瘀血阻络型、痰湿蕴结型和肝肾阴虚型3组,采用国际标准视力表检测患者的视力、光学相干断层成像技术(OCT)测量黄斑区视网膜厚度。结果:瘀血阻络型、痰湿蕴结型、肝肾阴虚型的分布频率依次为46.7%、30.7%、22.7%;而瘀血阻络型、痰湿蕴结型黄斑区厚度均明显大于肝肾阴虚型,差异均有显著性意义(P<0.05)。结论:特发性黄斑前膜术后以瘀血、痰湿标实证为突出表现,其黄斑区视网膜厚度明显增厚。

Objective： To explore the relationship between TCM syndrome patterns and retinal thickness of macular area of patients after idiopathic macular epiretinal membrane surgery. Methods.. Seventy-five patients were differentiated as the following three TCM syndrome patterns： blood-stasis blocking collaterals, accumulation of phlegm-damp, and yin deficiency of liver and kidney. Visual acuity was tested by International Standard Visual Acuity Chart, and retinal thickness of macular area was detected by optical coherence tomography （OCT）. Results： The distribution frequency of blood-stasis blocking collaterals, accumulation of phlegm-damp, and yin deficiency of liver and kidney was 46.7%, 30.7% and 22.7% respectively. The macular retinal thickness of in patients with blood-stasis blocking collaterals and accumulation of phlegm-damp was obviously thicker than in patients with yin deficiency of liver and kidney （P 〈 0.05）. Conclusion： Patients after idiopathic macular epiretinal membrane surgery have the dominant excess syndrome of blood stasis and phlegm-damp, which also have obviously increased macular retinal thickness.