金银花减压提取工艺研究

Study on Vacuum Extraction Process of Honeysuckle

目的:筛选金银花减压提取工艺条件。方法:以绿原酸的转移率为考察指标,采用正交试验法对加水量、真空度、时间、pH因素进行优选研究,并与温浸法、常压煎煮法进行比较。结果:金银花减压提取的最优工艺为加水量20倍(pH 5.0),真空度-0.070 mPa(温度75℃),提取2次,每次1 h。减压提取法优于温浸法和常压煎煮法。结论:该工艺稳定可行,对同性质的药材提取有一定的借鉴意义。

Objective： To select the best vacuum extraction process of honeysuckle. Method： Orthogonal design was used on the optimum extracting process to determine the effect of water dosage, vacuity, time, pH with the extracting rate of chlorogenic acid as maker,which compared with warm immersion and ordinary pressure refluxing extraction. Result：The optimal vacuum extracting process for chlorogenic acid was： adding 20 folds of water （ pH 5.0）, -0. 070 mPa （75 ℃） vacuum; extracted 2 times for 1 hour each time. And the decompressed refluxing extraction method was superior to the warm soaking method and the boiling method. Conclusion：The optimized extraction process is stable and feasible,and it offers a certain reference value for the same kind herbal to extract.