重型肝炎患者血糖、甲胎蛋白和胆碱脂酶检测的临床意义

Clinical sighificance of Blood glucose, AFP and cholinesterase levels on the early diagnosis and prognosis of severe hepatitis patients

目的探讨血糖、甲胎蛋白和胆碱脂酶水平对重型肝炎的诊断以及预后判断价值。方法回顾性分析慢性乙型肝炎、肝硬化失代偿、慢性重型肝炎、亚急性重型肝炎患者之间，以及重型肝炎好转组与死亡组之间血糖、甲胎蛋白、胆碱脂酶的差异。结果亚急性重型肝炎、慢性重型肝炎患者血糖和胆碱脂酶水平明显低于慢性乙型肝炎及肝硬化患者（均P〈0．05）；而甲胎蛋白水平显著高于慢性乙型肝炎（P〈0．01）；重型肝炎好转组血糖、甲胎蛋白、胆碱脂酶水平明显高于死亡组（均P〈0．05）。结论血糖、甲胎蛋白、胆碱脂酶检测对肝脏疾病的进展程度及预后估计有重要判断价值。

Objective To study clinical value of blood glucose, AFP and cholinesterase levels on the diagnosis and prognosis of severe hepatitis. Methods Retrospective analysis of chronic hepatitis B,cirrhosis,chronic severe hepatitis, subacute severe hepatitis was carried out. In severe hepatitis patients, between the improved group and death group, blood glucose, AFP, cholinesterase differences, evaluate blood glucose, alpha-fetoprotein, cholinesterase levels on the diagnosis and prognosis of severe hepatitis value were compared. Results Subacute severe hepatitis, chronic severe hepatitis patients and blood cholinesterase levels were significantly lower than that in patients with chronic hepatitis B and liver cirrhosis（ all P 〈 0.05 ） ;and alpha-fetoprotein level was significantly higher than the level of chronic hepatitis B patients（ P 〈 0. 01 ） ;improved levels of blood glucose in patients with severe hepatitis, AFP, cholinesterase levels were significantly higher than the level of death group （ all P 〈 0.05 ）. Conclusion Blood glucose, AFP, cholinesterase levels of liver disease progression and prognosis were important to determine the value.