中频脉冲穴位刺激对高血压早期肾损害患者血清白细胞介素水平的影响

The impact on serum interleukin-4 and interleukin-17 in patients with hypertension and early renal damage treated with IF pulse electrical stimulation on acupuncture points

目的探讨中频脉冲电穴位刺激对高血压早期肾损害患者血清白细胞介素-4（IL4）和白细胞介素-17（IL—17）的影响。方法选取100例确诊为高血压早期肾损害的患者，随机分为对照组与治疗组各50例，对照组子常规降压药物，治疗组在常规治疗的基础上加用中频脉冲穴位治疗，两组均对症治疗所合并的疾病，经治疗20d后，对比患者血清IL-4和IL-17的变化。结果治疗后治疗组患者血清IL-14和IL-17水平与对照组差异均有统计学意义（均P〈0．05）。结论中频脉冲电刺激肾俞、命门、关元等穴位，对IL-4和IL-17等早期肾损害指标有改善作用，可以减少对高血压的靶器官早期损害，协助降压并减少降压药物的用量。

Objective To discuss the impact on serum interleukin-4 and interleukin-17 in patients with hypertension and early renal damage treated with intermediate frequency If pulse electrical stimulation on acupuncture points. Methods Selected 100 patients diagnosed with early renal damage in hypertension, those were divided into control group and treatment group randomly ,50 patients in the control group treated with conventional antihypertensive drugs and symptomatic treatment of diseases, while the treatment group on the basis of conventional therapy plus IF pulse point therapy,20 days after treatment compared serum IL-4 and IL-17 levels. Results Treatment group, serum IL-14 and IL-17 levels were significantly lower than the control group （all P 〈 0.05 ）. Conclusion Shenshu, Mingmen, Guanyuan and other points by electrical stimulation pulse frequency, could make IL-4 ,IL-17 and other indicators of early renal damage improve the role, and reduce hypertension early target organ damage, and help reduce pressure and reduce the amount of antihypertensive drugs.