心脏X综合征与血尿酸水平的相关性研究

Relationship between cardiac syndrome X and serum uric acid level

目的研究心脏X综合征与血尿酸水平的关系。方法回顾性调查60例心脏X综合征患者、200名健康体检者血尿酸、血糖、血脂等指标水平,同时进行血尿酸与心脏X综合征的相关性、危险因素分析。结果心脏X综合征组尿酸水平为(418.64±46.78)μmol/L、血糖水平为(5.46±1.43)mmol/L与对照组[(336.45±34.98)μmol/L,(5.09±1.01)mmol/L]比较差异有统计学意义(均为P<0.05),两组血脂水平比较差异无统计学意义(P>0.05)。病例对照研究,表明尿酸与心脏X综合征的发生有关联(OR:4.19,95%CI:2.259～7.768,P<0.01)。结论血尿酸水平升高与心脏X综合征的发生具有一定的相关性。

Objective To study the relationship between cardiac syndrome X and serum uric acid level. Methods Sixty patients with cardiac syndrome X （ cardiac syndrome X group ） and 200 healthy subjects （ control group ） were retrospectively investigated, serum uric acid, blood sugar and lipid levels were measured in all subjects. Results Serum uric acid level was significantly higher in cardiac syndrome X group than in control group [ （418.64±46. 78）μmol/L vs. （336.45 ±34.98）μmol/L, P 〈 0.05 ]. Serum uric acid was associated with the occurrence of cardiac syndrome X （ OR ： 4. 19, 95% CI： 2. 259-7. 768, P 〈 0. 01 ）. Conclusion High serum level of uric acid might be an independent risk factor of cardiac X syndrome.