摘要
炭疽是由炭疽芽孢杆菌引起的一种人畜共患烈性传染病。炭疽菌主要通过释放炭疽毒素使宿主致病。炭疽毒素包括致死毒素和水肿毒素,这两种毒素是使炭疽感染者死亡的主要因素。该文综述了抗炭疽毒素小分子药物的研究进展。
Anthrax is a severe epidemic disease caused by Bacillus anthracis,and acts mainly by releasing anthrax toxin that consists of two toxins,lethal toxin（LT） and edema toxin（ET）,which are the primary factors of death.In this review the recent advances in the development of small molecule inhibitors of anthrax toxin are discussed.
出处
《军事医学》
CAS
2011年第1期67-72,共6页
Military Medical Sciences
关键词
炭疽
炭疽毒素
抑制剂
anthrax
anthrax toxin
inhibitors
