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舒芬太尼复合地塞米松用于骨科小儿术后镇痛的临床研究 被引量:1

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摘要 目的研究不同剂量的舒芬太尼复合地塞米松用于骨科小儿术后静脉镇痛的临床效果,旨在为小儿术后静脉镇痛提供一定的临床经验。方法选择全麻下实施骨科手术的患儿45例,ASA分级I—II级,所有手术均为择期患者,随机分成3组,每组15例:I组舒芬太尼2.0μg/kg,II组舒芬太尼1.5μg/kg+地塞米松150μg/kg,III组舒芬太尼2.0μg/kg+地塞米松150μg/kg。术后1,4,24,36h观察患儿心率、呼吸、血压、氧饱和度、进行镇痛和镇静评分、记录按压次数、计算舒芬太尼用量、检测术后1,24h空腹血糖。结果II、III组患儿在4,24h的镇痛评分和按压次数低于I组,有显著差异,Ⅱ、III组之间无显著差异,各组之间在1,36h时无显著差异;I组患儿舒芬太尼用量多于II、III组,有显著性差异,II、III组患儿之间无显著差异;3组患儿在各时间点心率、呼吸、血压、氧饱和度、镇静评分无显著差异;恶心:I、II组各2例(13.3%),III组1例(6.7%);嗜睡:I、III组各1例、II组2例;3组患儿术后血糖均高于术前,组问比较无显著差异。结论舒芬太尼1.5—2μg/kg+地塞米松150μg/kg应用于小儿镇痛是安全有效的,地塞米松减少了舒芬太尼用量,效果优于单纯的应用舒芬太尼。
出处 《中国中医药咨讯》 2011年第1期94-95,共2页
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