期刊文献+

芪苈强心胶囊对舒张性心力衰竭患者NT—proBNP的干预研究 被引量:2

下载PDF
导出
摘要 目的:探讨芪苈强心胶囊治疗舒张性心力衰竭的疗效及机制。方法:将70例舒张性心力衰竭患者随机分为对照者和治疗组,分别给予常规治疗和在常规治疗基础上加以芪苈强心胶囊,观察两组患者临床疗效及血N末端脑钠肽前体(NT—pmBNP)的变化。结果:两组均能明显改善患者的心功能及生活质量(P〈0.05),但治疗组优于对照组(P〈0.05);治疗组血NT—proBNP与患者的心功能及血超敏C反应蛋白水平明显相关(P〈0.05)。结论:芪苈强心胶囊能改善患者的心功能、提高生活质量,机制可能为改善心衰患者的炎性反应。
作者 刘葆华
出处 《中国中医药咨讯》 2011年第3期13-13,共1页
  • 相关文献

参考文献2

二级参考文献15

  • 1Gabay C, Kushner I. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med,1999,340:448-454.
  • 2Alonso-Martinez JL,Llorente-Diez B,Echegaray-Agara M, et al. C-reactive protein as a predictor of improvement and readmission in heart failure. Eur J Heart Fail, 2002,49: 331-336.
  • 3Kitamura K, Kangawa K, kawamoto M, et al. Adrenomedullin:a novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun, 1993,192: 553-560.
  • 4Bettencourt P, Ferreira A, Dias P, et al. Evaluation of brain natriuretic peptide in the diagnosis of heart failure. Cardiology, 2000,93:19-25.
  • 5Suzuki T,Yamaoki K, Nakajima O, et al. Screening for cardiac dysfunction in asymptomatic patients by measuring B-type natriuretic peptide levels. Jpn Heart J,2000,41:205.
  • 6Field SJ. E2F-1 functions in mice to promote apopote apoptosis and suppress proliferation. Cell, 1996,85: 54.
  • 7Fedak PW, Svetlana M, Altamentova SM, et al. Matrix remodeling in experimental and human heart failure: a possible regulatory role for TIMP-3. Am J Physiol Heart Cire Physiol, 2003,284: 626-634.
  • 8Beinhardt D , Sigusch HH, Hen BE, et al. Cardiac remodeling in end stage heart failure: upregulation of matrix metalloproteinase (MMP) irrespective of the underlying disease, and evidence for a direct inhibitory effect of ACE inhibitors on MMP. Heart, 2002, 88:525-530.
  • 9Levine M, Kalman J, Mayer L, et al. Elevated circulating levels of tumor necrosis factor in severe chronic heart failure. N Eng J Med, 1990,323:236-241.
  • 10Torr-Amione G, Kapadia S, Benedict C, et al. Proinflammatory cytokine levels in patients with depressed left ventricular ejection fraction: a report from the studies of left ventricular dysfunction(SOLVD). J Am Coll Cardiol, 1996,27:1201-1206.

共引文献8

同被引文献12

引证文献2

二级引证文献12

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部