Organocatalytic asymmetric allylic alkylation of sulfonylimidates with Morita-Baylis-Hillman carbonates 被引量：1

Organocatalytic asymmetric allylic alkylation of sulfonylimidates with Morita-Baylis-Hillman carbonates

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摘要 The asymmetric allylic alkylation reaction of sulfonylimidates with various Morita-Baylis-Hillman (MBH) carbonates was accomplished by the catalysis of commercially available cinchona alkaloids catalyst (DHQD)2AQN.The corresponding allylic alkylation products were obtained in good yields with high stereoselectivities (up to 99% ee,89:11 dr). The asymmetric allylic alkylation reaction of sulfonylimidates with various Morita-Baylis-Hillman （MBH） carbonates was accomplished by the catalysis of commercially available cinchona alkaloids catalyst （DHQD）2AQN.The corresponding allylic alkylation products were obtained in good yields with high stereoselectivities （up to 99% ee,89：11 dr）.

作者 PENG Jing,CUI HaiLei & CHEN YingChun Key Laboratory of Drug-Targeting and Drug Delivery System,Ministry of Education Department of Medicinal Chemistry,West China School of Pharmacy,Sichuan University,Chengdu 610041,China

出处《Science China Chemistry》 SCIE EI CAS 2011年第1期81-86,共6页 中国科学（化学英文版）

基金 financially Supported by the National Natural Science Foundation of China (20772084)

关键词烷基化反应烯丙基不对称碳酸盐有机催化立体选择性催化作用碱催化剂 organocatalysis asymmetric allylic alkylation sulfonylimidates Morita-Baylis-Hillman carbonates cinchona alkaloids

分类号 O643.32 [理学—物理化学]

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Organocatalytic asymmetric allylic alkylation of sulfonylimidates with Morita-Baylis-Hillman carbonates 被引量：1

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