摘要
The asymmetric allylic alkylation reaction of sulfonylimidates with various Morita-Baylis-Hillman (MBH) carbonates was accomplished by the catalysis of commercially available cinchona alkaloids catalyst (DHQD)2AQN.The corresponding allylic alkylation products were obtained in good yields with high stereoselectivities (up to 99% ee,89:11 dr).
The asymmetric allylic alkylation reaction of sulfonylimidates with various Morita-Baylis-Hillman (MBH) carbonates was accomplished by the catalysis of commercially available cinchona alkaloids catalyst (DHQD)2AQN.The corresponding allylic alkylation products were obtained in good yields with high stereoselectivities (up to 99% ee,89:11 dr).
基金
financially Supported by the National Natural Science Foundation of China (20772084)
关键词
烷基化反应
烯丙基
不对称
碳酸盐
有机催化
立体选择性
催化作用
碱催化剂
organocatalysis
asymmetric allylic alkylation
sulfonylimidates
Morita-Baylis-Hillman carbonates
cinchona alkaloids