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炎症标志物与急性冠状动脉综合征的研究进展(综述)

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摘要 炎症在急性冠状动脉综合征(ACS)形成过程中起关键作用,与心血管疾病的发生、发展、病理生理变化、诊断、治疗和预后密切相关。炎症标志物(1)C反应蛋白(CRP),(2)白介素(IL),(3)CD40-CD40L系统,(4)髓过氧化物酶(MPO),(5)妊娠相关性血浆蛋白A(PAPP-A),(6)核因子κB(NF-κB)在ACS的演变过程中起重要作用。其病理生理基础是冠状动脉粥样斑块不稳定,发生破裂继之血栓形成,部分或完全堵塞病变的血管,从而导致不同程度的心肌缺血、损伤,发生一系列冠脉病变,ACS与炎症标志物的促发,介导相关联。本文就ACS炎症标志物的研究进展及临床意义作一综述。
作者 孙宝强
机构地区 天津市河东区中医医院内科
出处 《中国城乡企业卫生》 2011年第1期22-24,共3页 Chinese Journal of Urban and Rural Enterprise Hygiene
关键词 动脉粥样硬化 急性冠状动脉综合征 炎症标志物
分类号 R543.3 [医药卫生—心血管疾病]
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中国城乡企业卫生
2011年 第1期

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