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DOP及PD方案术前诱导化疗在口腔鳞癌治疗中的应用 被引量:1

Preoperative Inductive Chemotherapy with DOP or PD Regimen in Oral Squamous Cell Carcinoma
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摘要 对采用DOP方案及PD方案术前诱导化疗的149例口腔鳞癌的疗效进行观察分析。采用DOP方案治疗95例,PD方案治疗54例,药物总有效率分别为85.3%、79.6%。化疗后10~14d施行手术治疗。3a、5a生存率分别为72.8%、68.2%。术前采用DOP或PD方案治疗口腔鳞癌均能达到诱导化疗的目的。对体质较好,特别是有淋巴结转移者,采用DOP方案较为适宜,对于体质较差者,则可采用PD方案。 The clinical response of 149 cases with oral squamous cell carcinoma to preoperative chemotherapy with DOP or PD regimen was observed and analyzed.DOP regimen(95 cases) resulted in a 85.3% response rate,PD regimen(54 cases) resulted in a 79.6% response rate.All cases received operation in 10~14 days after chemotherapy.Follow up survey showed the survival rate of 3,5 years was 72.8%,68.2% respectively.The authors consider:that the preoperative inductive chemotherapy with DOP or PD regimen was effective for oral squamous cell carcinoma.DOP regimen was suitable for the cases with good physique,especially the cases with lymphogenous metastasis and PD regimen was suitable for the cases with bad physique.
机构地区 河南省肿瘤医院
出处 《实用癌症杂志》 1999年第3期211-212,共2页 The Practical Journal of Cancer
关键词 口腔肿瘤 鳞状细胞癌 药物疗法 DOP方案 PD方案 Oral neoplasms Carcinoma Squamous cell Drag therapy
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