季节模式、胎儿性别对自然早产影响的分析

Analysis on effects of seasonal pattern and fetal sex on spontaneous preterm birth

目的:收集11年自然早产病例,分析季节模式、胎儿性别对自然早产的影响。方法:回顾性收集1997～2007年自然早产4 081例,比较11年来自然早产率,比较不同的季节和性别对自然早产的影响。结果:随着时间的发展,自然早产率逐渐增加;自然早产随季节的变化而变化,8～12月和1～2月自然早产率处于高峰期;四季比较,秋冬季自然早产明显高于夏季,差异存在统计学意义(P<0.0071),冬季自然早产明显高于春季,差异存在统计学意义(P<0.0071),而自然早产在春季与夏秋季及秋季与冬季间差异没有统计学意义(P>0.0071);自然早产在胎儿性别间差异存在统计学意义,男性胎儿发生自然早产明显高于女性胎儿(P<0.05)。结论:随着时间的发展,自然早产率逐渐增加,自然早产与季节模式有关,自然早产与胎儿的性别有关。

Objective：To collect the cases with spontaneous preterm birth in recent eleven years,analyze the effects of seasonal pattern and fetal sex on spontaneous preterm birth.Methods：4 081 cases with spontaneous preterm birth from 1997 to 2007 were collected retrospectively,the rates of spontaneous preterm birth in recent eleven years were compared,the effects of different seasonal patterns and fetal sexes on spontaneous preterm birth were compared.Results：The rate of spontaneous preterm birth in recent eleven years increased gradually,changing with seasons,the rate of spontaneous preterm birth peaked from August to December,from January to February;the rates of spontaneous preterm birth in autumn and winter were significantly higher than that in summer（P〈0.0071）,the rate of spontaneous preterm birth in winter was significantly higher than that in spring（P〈0.0071）,there was no significant difference in rate of spontaneous preterm birth between spring and summer,autumn,as well as between autumn and winter（P〉0.0071）,there was significant difference in rate of spontaneous preterm birth between male fetuses and female fetuses,the rate of spontaneous preterm birth in male fetuses was significantly higher than that in female fetuses（P〈0.05）.Conclusion：The rate of spontaneous preterm birth in recent eleven years increases gradually,spontaneous preterm birth is related to seasonal pattern and fetal sex.