海藻酸钠微球经子宫动脉栓塞治疗子宫腺肌病疗效及对卵巢功能的影响

Clinical efficacy of KMG uterine artery embolization in treatment of adenomyosis and the effect on ovarian function

目的:探讨海藻酸钠微球经子宫动脉栓塞治疗子宫腺肌病疗效及对卵巢功能的影响。方法:120例经超声或MRI明确诊断的子宫腺肌病患者行双侧子宫动脉栓塞,测定术前、术后黄体生成素、促卵泡素,雌二醇水平变化;随访痛经缓解率、异常月经改善率和子宫体积大小变化。结果:120例患者共进行了238次子宫动脉栓塞术。96例术后痛经完全消失,11例明显缓解,5例复发,临床显效率95.53%;月经明显减少,周期恢复正常;贫血患者术后6个月恢复正常;子宫体积呈进行性明显缩小;手术前后黄体生成素、促卵泡素、雌二醇差异无显著性。结论:海藻酸钠微球经子宫动脉栓塞治疗子宫腺肌病,近期效果显著,具有微创、安全、疗效好的特点。

Objective：To explore the clinical efficacy of KMG uterine artery embolization in treatment of adenomyosis and the effect on ovarian function.Methods：120 cases with adenomyosis diagnosed by ultrasound and MRI received bilateral uterine artery embolization,the changes of luteinizing hormone,follicle-stimulating hormone and estradiol levels before and after operation were detected;the remission rate of dysmenorrhea,the remission rate of abnormal menstruation and changes of uterine volume were followed up.Results：120 cases received uterine artery embolization for 238 times;after operation,dysmenorrhea disappeared in 96 cases,dysmenorrhea relieved obviously in 11 cases,5 cases recurred,the clinical effective rate was 95.53%;the menstrual amount decreased significantly,and the menstrual cycle returned to normal;at 6 months after operation,the cases with anemia returned to normal;the uterine volume decreased progressively;there was no significant difference in levels of luteinizing hormone,follicle-stimulating hormone and estradiol before and after operation.Conclusion：The short-term therapeutic effectiveness of KMG uterine artery embolization is obvious,the method has the characteristics of minimal invasion,safety and good effectiveness.