中西药联合生活方式调整对肥胖型多囊卵巢综合征生殖内分泌及促排卵的影响被引量：9

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摘要目的:探讨中西药联合生活方式调整治疗肥胖型多囊卵巢综合征(PCOS)的临床疗效。方法:测定126例肥胖型PCOS的生殖内分泌及一般指标,并与56例无肥胖非PCOS不孕患者进行比较。给予中西药联合生活方式调整治疗6个月,共有100例完成治疗。观察其治疗前后相关指标的变化及随后促排卵情况。结果:126例肥胖型PCOS患者的基础促黄体生成素(LH)、促黄体生成素与卵泡刺激素比值(LH/FSH)、睾酮(T)、体重指数(BMI)、腰臀围比值(WHR)均高于无肥胖非P-COS不孕患者(P<0.05);经多方案治疗后,LH、T、LH/FSH及BMI、WHR均明显下降,差异有统计学意义;卵巢体积减小(P<0.05),排卵率82.26%,妊娠率33.00%。结论:中西药联合生活方式调整治疗肥胖型PCOS,可有效改善其生殖内分泌紊乱,增加促排卵药物的敏感性,提高排卵率及妊娠率,使部分肥胖型PCOS患者恢复排卵和妊娠。

作者张秀青王爱华高艳霞

机构地区河北省邯郸市妇幼保健院不孕不育症科

出处《中国妇幼保健》 CAS 北大核心 2011年第3期389-390,共2页 Maternal and Child Health Care of China

关键词多囊卵巢综合征中西药生活方式排卵

分类号 R711.6 [医药卫生—妇产科学]

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