凌晨高血压患者心率变异性及室性心律失常发生情况分析

Analysis of heart rate variability and the incidence of ventricular arrhythmia in essential hypertension patients with morning blood pressure surge

目的:利用动态心电图测定凌晨高血压(Morning blood pressure surge,MBPS)患者的心率变异性(Heart rate variability,HRV)及室性心律失常的发生情况。方法:连续入选于2009年6月至2010年5月我院住院的凌晨高血压患者50例,同时选择年龄、性别相匹配的非凌晨高血压患者50例作为对照组,监测其24 h动态心电图,行心率变异性分析及记录室性心律失常发生情况。结果:凌晨高血压患者的心率变异性各指标(SDNN、SDANN、SDNN-Index、RMSSD、PNN50)均低于非凌晨高血压组,而室性心律失常的发生多于非凌晨高血压组,且差异统计学意义。结论:凌晨高血压的自主神经功能受损更为明显,该类患者的室性心律失常发生明显增多。

Objective：To analyze heart rate variability（HRV） and the incidence of ventricular arrhythmia in essential hypertension patients with morning blood pressure surge（MBPS）.Methods：A total of 50 consecutive essential hypertension patients with morning blood pressure surge and 50 age-and gender-matched subjects with essential hypertension（control group） were enrolled in the present study at our institution from June 2009 to May 2010.The parameters of heart rate variability and the incidence of ventricular arrhythmia in every time-span were observed though 24 hours holter monitoring electrocardiogram.Results：The parameters of HRV（SDNN,SDANN,SDNN-Index,RMSSD,PNN50） in MBPS group were significantly lower than control group.The incidence of ventricular arrhythmia for 24 hours in MBPS group was obviously higher than that in control group.Conclusion：Autonomic nerve dysfunction is more obviously occurred in essential hypertension patients with MBPS and the occurrence of ventricular arrhythmias is also significantly increased.