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miR-125a在先天性巨结肠中的表达及意义 被引量：3

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摘要 MicmRNA（miRNA）是近几年在真核生物中发现的一类具有调控功能的非编码RNA，大小约为21～25个碱基的单链小分子RNA。miRNA能调节生物体生长、发育和疾病发生过程中有关基因的表达，推测这种小分子调控人类近1／3的基因，平均每个miRNA可调节人类200种不同的mR—NA表达，并且多个miRNA能够协调调节一些特殊的靶基因。大量实验证明在多种疾病中，
作者 高红 苏真伟 伍美 张志波 黄英 王维林
机构地区 中国医科大学附属盛京医院卫生部小儿先天畸形重点实验室
出处 《中华小儿外科杂志》 CSCD 北大核心 2011年第2期158-160,共3页 Chinese Journal of Pediatric Surgery
基金 国家自然科学基金资助项目（编号：30772277）
关键词 先天性巨结肠 非编码RNA miRNA 小分子RNA 分子调控 可调节 靶基因 真核生物
分类号 R363 [医药卫生—病理学]
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参考文献15

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共引文献22

同被引文献36

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二级引证文献9

中华小儿外科杂志
2011年 第2期

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