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自组装病毒样纳米结构与超灵敏生物传感 被引量:2

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摘要 在生命科学中,分子自组装是一个十分重要的前沿研究领域。它本身蕴藏着生命发生的奥妙,维持着生命结构的形成和各种复杂生物学功能的执行。而病毒是最简单的生命体,它依赖于宿主进行复制、自组装形成自我,并繁殖后代,是一种典型的分子自组装体。多年来,人们对病毒的自组装行为和机制作了很多深入的研究,特别是利用病毒的体外自组装对病毒组装过程进行操纵、改造,制备各种自组装病毒样功能纳米结构,并将其广泛运用于医学、药学、诊断学、化工和电子等领域。作者将最近10年来病毒样纳米结构在超灵敏生物传感应用方面的进展进行了归纳总结,阐述和探讨了自组装病毒样纳米结构在生物传感领域中的应用。
出处 《东南大学学报(医学版)》 CAS 2011年第1期92-99,共8页 Journal of Southeast University(Medical Science Edition)
基金 卫生部重大专项资助课题(2009zx10004-107)
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