经阴道彩色多普勒超声在中晚期宫颈癌诊治中的应用价值

Application value of transvaginal color Doppler ultrasonography in diagnosis and treatment of mid-advanced cervical carcinoma

目的探讨经阴道彩色多普勒超声(CDFI)在中晚期宫颈癌的诊断及评价治疗效果中的应用价值。方法应用经阴道CDFI对我院75例中晚期宫颈癌患者在介入治疗或放疗前后进行超声检查。结果 75例经阴道CDFI提示宫颈癌的患者经病理诊断证实。治疗后58例肿瘤直径明显缩小至消失,与治疗前比较差异有统计学意义(P<0.01)。治疗前所有病例肿瘤周边及其内部血流信号丰富,治疗后58例肿瘤周边及其内部血流信号逐渐减少至消失;治疗前后宫颈肿瘤血流阻力指数(RI)、血流速度(Vs)比较差异有统计学意义(P<0.01);治疗前75例患者较容易检测到子宫动脉速度,RI值较低,治疗后74例子宫动脉Vs有不同程度的降低,RI值升高,治疗前后子宫动脉血流RI、Vs比较差异有统计学意义(P<0.01)。结论经阴道CDFI可对宫颈癌的术前诊断,介入治疗和放疗的疗效判断提供重要信息,有助于协助临床治疗方案的制定,提高治疗效果。

To investigate the application value of transvaginal color Doppler ultrasonography in diagnosis and therapeutic effects evaluation of mid - advanced cervical carcinoma. Methods Transvaginal color Doppler ultrasonography was performed on 75 patients with mid - advanced cervical carcinoma before and after treatment with interventional therapy and radiotherapy, the results were comparatively analyzed. Results Seventy-five patients with cervical carcinoma were performed with transvaginal color Doppler ultrasonography and confirmed by pathology. Tumor diameter in 58 cases after treatment was reduced gradually and disappeared, there was significant difference comparing with that before treatment （ P 〈 0.01 ）. In all cases, blood flow signals within and around the tumors were abundant before treatment, while reduced gradually and disappeared in 58 cases after treatment, there was significant difference in blood flow RI and Vs of cervical carcinoma comparing with that before treatment （P 〈0.01 ）. The flow velocity of uterine artery was easy to be detected in 75 cases before treatment, and RI was low, while after treatment, the flow velocity of uterine artery in 74 cases was decreased in varying degrees, and RI was increased, there was significant difference in blood flow RI and Vs of uterine artery comparing with that before treatment （ P 〈 0.01 ）. Conclusion Transvaginal color Doppler uhrasonography can provide important information for preoperative diagnosis of cervical carcinoma, therapeutic effect evaluation of interventional therapy and radiotherapy, it can help to make clinical treatment plan and increase the therapeutic efficacy.