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bHLH和Hox基因对GABA能神经元诱导分化研究进展 被引量：2

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摘要 γ-氨基丁酸（gamma-aminobutyric acid,GABA）是神经系统主要的抑制性神经递质,在中枢神经系统中发挥重要的作用,幼年时期兴奋性神经递质占主导地位,随着年龄的增长,兴奋性和抑制性神经递质逐渐达到平衡,
作者 龙乾发 刘卫平
机构地区 第四军医大学西京医院神经外科
出处 《中华神经外科疾病研究杂志》 CAS 2010年第6期564-566,共3页 Chinese Journal of Neurosurgical Disease Research
关键词 bHLH基因 HOX基因 GABA能神经元
分类号 R329.2 [医药卫生—人体解剖和组织胚胎学]
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参考文献19

  • 1Hachiya Y,Takashima S.Development of GABAergic neurons and their transporter in human temporal cortex[J].Pediatr Neurol,2001,25(5):390-396.
  • 2Sperk G,Furtinger S,Schwarzer C,et a1.GABA and its receptors in epilepsy[J].Adv Exp Med Biol,2004,548:92-103.
  • 3Kageyama R,Ohtsuka T,Hatakeyama1 J,et al.Roles of bHLH genes in neural stem cell differentiation[J].Exp Cell Res,2005,306(2):343-348.
  • 4Miyoshi G,Bessho Y,Yamada S,et al.Identification of a novel basic helix-loop-helix gene,Heslike,and its role in GABAergic neurogenesis[J].J Neurosci,2004,24(14):3672-3682.
  • 5Chien CT,Hsiao CD,Jan LY,et al.Neuronal type information encoded in the basic-helix-loop-helix domain of proneural genes[J].Proc Natl Acad Sci USA,1996,93(23):13239-13244.
  • 6Nakhai H,Sel S,Favor J,et al.Ptf1a is essential for the differentiation of GABAergic and glycinergic amacrine cells and horizontal cells in the mouse retina[J].Development,2007,134(6):1151-1160.
  • 7Hori K,Cholewa-Waclaw J,Nakada Y,et al.A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling[J].Genes Dev,2008,22(2):166-178.
  • 8Euiseok J,Cheuk T,Randall R,et al.In vivo analysis of Ascl1 defined progenitors reveals distinct developmental dynamics during adult neurogenesis and gliogenesis[J].J Neurosci,2007,27(47):12764-12774.
  • 9Guimera J,Weisenhorn D,Wurst W.Megane/Heslike is required for normal GABAergic differentiation in the mouse superior colliculus[J].Development,2006,133(19):3847-3857.
  • 10Joa AY,Park CH,Aizawa S,et al.Contrasting and brain region-specific roles of neurogenin2 and mash1 in GABAergic neuron differentiation in vitro[J].Exp Cell Res,2007,313(19):4066-4081.

二级参考文献34

  • 1Ferrier DE, Minguillon C. Evolution of the Hox/ParaHox gene clusters [J]. lnt J Dev Biol, 2003, 47(7 -8) : 605 -611.
  • 2Valentine JW, Jablonski D. Morphological and developmental macroevolution: a paleontological perspective [ J ]. Int J Dev Biol, 2003, 47(7 -8) : 517 -522.
  • 3Arenkiel BR, Gaufo GO, Capecchi MR, et al. Hoxbl neural crest preferentially form glia of the PNS [J]. Dev Dyn, 2003, 227(3) : 379 - 386.
  • 4Papageorgiou S. A cluster translocation model may explain the collinearity of Hox gene expressions [ J ]. Bioessays, 2004, 26 ( 2 ) : 189 - 195.
  • 5Lang D, Powell SK, Plummcr RS, et al. PAX genes: roles in development, pathophysiology and cancer [ J ]. Biochem Phannacol, 2007, 73(1): 1 -14.
  • 6Widlund HR, Fisher DE. Microphthalamia-associated transcription factor: a critical regulator of pigment cell development and survival [J]. Oncogene, 2003, 22(20): 3035-3041.
  • 7Homyak TJ, Hayes DJ, Chiu LY, et al. Transcription factors in melanocyte development: distinct roles for Pax-3 and Miff [ J]. Meeh Dev, 2001, 101(1 -2): 47-59.
  • 8Dawid IB, Breen JJ, Toyama R. LIM domains: multiple roles as adapters and functional modifiers in protein interactions [ J ]. Trends Genet, 1998, 14(4) : 156- 162.
  • 9Shawlot W, Behringer RR. Requirement for Liml in head-organizer function [J]. Nature, 1995, 374(6521 ) : 425 -430.
  • 10Porter FD, Drago J, Xu Y, et al. Lhx2, a LIM homeobox gene, is required for eye, forebrain, and definitive erythrocyte development [ J ]. Development, 1997, 124 ( 15 ) : 2935 - 2944.

共引文献10

同被引文献17

  • 1陈锦华,杨辉,尹昌林,张治元,刘仕勇,何家全,高方友.BMP2在SVZa神经干细胞向GABA能神经元分化中的调控作用[J].第三军医大学学报,2007,29(8):699-701. 被引量：7
  • 2Hughes L F, Turner J G, Parrish J L, et al. Processing of broadband stimuli across A1 layers in young and aged rats [ J]. Hear Res, 2010,264(1/2) : 79 -85.
  • 3Nagase T, Matsumoto D, Nagase M, et al. Neurospheres from human adipose tissue transplanted into cultured mouse embryos can contribute to craniofacial morphogenesis: a preliminary report [ J ]. J Craniofac Surg, 2007, 18(1) : 49 -53.
  • 4Xu Y, Liu Z, Liu L, et al. Neurospheres from rat adipose-derived stem ceils could be induced into functional Schwann ceU-like cells in vitro [J]. BMC Neurosci, 2008, 9:21 - 31.
  • 5Xu R, Jiang X, Guo Z, et al. Functional analysis of neuron-like cells differentiated from neural stem ceils derived from bone marrow stroma ceils in vitro [ J ]. Cell Mol Neurobiol, 2008, 28 (4) : 545 - 558.
  • 6Lopatina T, Kalinina N, Karagyaur M, et al. Adipose-derived stem cells stimulate regeneration of peripheral nerves: BDNF secreted by these ceils promotes nerve healing and axon growth de novo [ J ]. PLoS One, 2011, 6(3) : e17899.
  • 7Kuo Y R, Chen C C, Goto S, et al. Modulation of immune response and T-cell regulation by donor adipose-derived stem ceils in a rodent hind-limb allotransplant model [ J ]. Plast Reconstr Surg, 2011, 128 (6) : 661e -672e.
  • 8Philips B J, Marra K G, Rubin J P. Adipose stem cell-based soft tissue regeneration[J]. Expert Opin Biol Ther, 2012, 12(2) : 155 - 163.
  • 9Yang C , Li D, Wen Z, et al. Transplanted adipose-derlved stem cells delay D-galactose-induced aging in rats[ J]. Neural Regen Res, 2011,6(34) : 2673 -2680.
  • 10Kang S K, Putnam L A, Ylostalo J, et al. Neurogenesis of Rhesus adipose stromal cells[J]. J Cell Sci, 2004, 117(Pt 18) : 4289 - 4299.

引证文献2

二级引证文献1

中华神经外科疾病研究杂志
2010年 第6期

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