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乳腺原发性鳞状细胞癌的临床病理分析

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摘要 目的探讨乳腺原发性鳞状细胞癌(PSCC)的临床和病理特征。方法分析5例乳腺PSCC患者的临床特点,肿瘤大体和镜下特征,免疫组化结果,及患者的预后。结果 5例女性患者发病年龄38~78岁,多表现为无痛性乳腺肿块,腋窝淋巴结均无转移。免疫组化:雌激素(ER)、孕激素(PR)与人表皮生长因子受体(HER)2均阴性表达,p63、细胞角蛋白(CK)5/6及高分子量角蛋白(34βE12)均阳性表达。随访4例,1例术后9年死亡,3例随访6~9个月至今情况良好。结论乳腺PSCC有不同于乳腺浸润性导管癌的HE和免疫组化表达特点,确诊需经严格的病理学诊断。
出处 《江苏医药》 CAS CSCD 北大核心 2010年第24期2955-2956,F0002,共3页 Jiangsu Medical Journal
基金 江苏省人民医院临床新技术新项目基金资助
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