摘要
目的:探讨慢性牙周炎患者血清C反应蛋白(CPR)、E-选择素水平的变化及其临床意义。方法:选择143例慢性牙周炎患者,用免疫比浊法测定血清CPR,用酶联免疫吸附反应法(ELISA)测定血清E选择素水平,并和正常对照组比较。结果:慢性牙周炎患者血清CPR、E选择素水平增高,和牙周正常者比较(P<0.01)。结论:慢性牙周炎患者血清CPR、E-选择素的水平升高,是牙周炎促使冠心病发生发展的的重要物质基础。
Objective:To explore the expression of serums C-reactive protein(CRP)and E-selestin in patients with chronic periodontitis.Method:the blood serum was obtained from 143 patients with chronic periodontitis.As a control,blood serum was also obtained from 142 subjects without periodontitis.CRP was determined by Immunoturbidimetric assay and E-selectin was determined by sensitive enzyme-linked immunosorbent assay.Result:The levels of CRP and E-selestin in the blood serum of chronic periodontitis was higher than that in health control subjects.Conclusion:In this study,we were able to show that chronic periodontitis significantly affects the levels of serum CRP and E-selectin.
出处
《临床口腔医学杂志》
2010年第12期710-712,共3页
Journal of Clinical Stomatology
基金
十堰市科技攻关项目资助(2005031D)