中药面膜结合皮肤护理治疗面部烧伤后色素沉着

Treatment of facial pigmentation after burns with traditional Chinese medicine mask and skin care

目的 观察中药面膜结合皮肤护理治疗面部烧伤后色素沉着的效果.方法 选择2009年1月-2010年6月笔者单位收治的面部烧伤后色素沉着患者41例,按就诊顺序分为治疗组（奇数序号）26例和对照组（偶数序号）15例.给予洗面、局部按摩及蒸气喷雾等综合皮肤护理后,治疗组与对照组分别采用笔者单位自行研制的中药面膜和市售普通美容面膜外敷,干透后去除,隔日1次,10次为1个疗程,持续治疗3个疗程.于治疗前及各疗程末采用温哥华色素瘢痕评定量表测定患者皮肤色差,以计算机图像分析技术测量色素沉着区皮肤图像灰度值.统计各疗程末医患双方满意度,记录不良反心情况,比较2组总体疗效.对数据行x2检验或t检验.结果 治疗前2组患者皮肤色差及图像灰度值相近（t值分别为0.800和0.694,P值均大于0.05）.治疗组各疗程末皮肤色差、图像灰度值及医患双方满意度均优于对照组.3个疗程结束后,治疗组及对照组皮肤色差得分分别为（0.5±0.4）分和（1.1±0.6）分,图像灰度值分别为55±5和66±6,组间比较差异均有统计学意义（t值分别为3.389和5.102,P值均小于0.01）.治疗组总有效率为92.3%,明显优于对照组的53.3%（x^2=6.31,P＜0.05）.治疗过程中末见中药面膜引起的过敏反应.结论 中药面膜结合皮肤护理是治疗面部烧伤后色素沉着的有效方法.

Objective To observe the effects of traditional Chinese medicine mask combined with skin care in the treatment of facial pigmentation after burns. Methods Forty-one patients with facial pigmentation after burns hospitalized from January 2009 to June 2010 were enrolled and divided into treatment group （ n =26, odd number） and control group （ n = 15, even number） according to the visiting order.After cleaning, massaging, and steam spraying to faces, patients in treatment and control groups were respectively treated with traditional Chinese medicine mask developed by physicians in our hospital and common commercial beauty mask. Masks were removed when they became completely dry. The treatment was repeated every other day. Ten times made up a course of treatment. Three consecutive courses were carried out on each patient. Before treatment and at the end of each course, the skin color differences were measured with Vancouver Pigmented Scar Scale; image gray scale value of pigmented skin was measured with image analysis technique. Satisfaction degree acknowledged by both patients and physicians were recorded at the end of each course; adverse effects were recorded; and the overall efficacy between two groups was compared.Data were processed with chi-square test or t test. Results Skin color differences、 image gray scale value of patients in treatment group were close to those in control group before treatment （ with t value respectively 0. 800 and 0. 694, P values all above 0.05 ）. Skin color differences, image gray scale value, and satisfaction degree acknowledged by both patients and physicians in treatment group were better than those in control group at the end of each course. At the end of the third course of treatment, the skin color differences in treatment and control groups scored 0. 5 ±0.4 and 1. 1 ± 0. 6, respectively, with image gray scale value of 55 ± 5 and 66 ± 6, respectively, which were statistically different from each other （ with t value respectively 3. 389 and 5. 102, P values all below 0.01 ）. The overall efficacy of the treatment group was 92.3%, which was much better than that of the control group （53.3% , x 2= 6.31, P 〈 0. 05 ）. No allergy caused by the traditional Chinese medicine mask was observed during the treatment. Conclusions The traditional Chinese medicine mask combined with skin care is effective for the treatment of facial pigmentation after burns.