我院ICU病房院内下呼吸道感染病原菌分布及耐药性分析

Pathogenic Distribution and Antibacterial Resistance of Lower Respiratory Tract Nosocomial Infection in ICU of Our Hospital

目的:探讨ICU院内下呼吸道感染的病原学特点及防治策略,指导临床合理应用抗菌药的。方法:对132例ICU院内下呼吸道感染患者,取深部痰液进行培养并做药敏试验。结果:共检出病原菌156株,革兰阴性(G-)杆菌占66.7%,革兰阳性(G+)球菌占21.8%,真菌占11.5%。G-杆菌是下呼吸道感染的主要致病菌,细菌耐药情况严重。结论:监测ICU病原菌种类及其耐药性的变化,对合理使用抗菌药物、改善危重病人预后有重要意义。

OBJECTIVE： To explore the pathogenic features and the preventive strategies of lower respiratory tract nosocomial infection in ICU, and to guide use of antibiotics in the clinic. METHODS： Microbial culture of deep sputum and drug sensitive tests were conducted among 132 cases of lower respiratory tract nosocomial infection in ICU. RESULTS： 156 strains of pathogen were obtained, of which 66.7% was Gram-negative bacteria, 21.8% was Gram-positive bacteria and 11.5% was fungi. Gram-nega- tive bacteria were the main pathogens which induced lower respiratory tract nosocomial infection. Drug resistance was serious. CONCLUSION： The type and drug resistance of pathogen in ICU should be monitored, which play an important role for rational use of antibacterial and the improvement of prognosis on critically patients.