炎症介质与肥胖和多囊卵巢综合征

Relationships between inflammatory mediators, obesity and polycystic ovary syndrome

多囊卵巢综合征是育龄期妇女常见的内分泌疾病之一，且伴有高发病率的心血管疾病。多囊卵巢综合征患者的肥胖多为腹型肥胖，患者的肥胖与其慢性低度炎症和炎性细胞因子的增多有关。该文对多囊卵巢综合征患者的脂肪分布、脂肪细胞功能障碍及炎性标志物之间的潜在联系进行了论述。

Polycystic ovary syndrome（PCOS） is a common endocrine disorder of women of chidbearing age and the women with PCOS are usually associated with higher risks of cardiovascular diseases. Obesity, mainly visceral adiposity, of women with PCOS is associated with chronic low-grade inflammation and raised levels of inflammatory cytokines. In this paper, potential relationships between fat distribution, adipocyte dysfunction and altered inflammatory markers of patients with PCOS were explored.