呼吸道感染患儿血清肌酸激酶同工酶和羟丁酸脱氢酶的改变及临床意义

Variation and clinical significance of serum CK-MB and HBDH in children with respiratory infections

目的:探讨呼吸道感染患儿血清肌酸激酶同工酶(CK-MB)和羟丁酸脱氢酶(HBDH)的改变及临床价值。方法:采用免疫抑制法分别测定94例呼吸道感染患儿和100例健康儿血清CK-MB和HBDH水平。结果:呼吸道感染组患儿血清CK-MB和HBDH水平与正常对照组比较明显升高,相比较差异有统计学意义(P<0.05);血清CK-MB和HBDH水平随着感染程度加重而升高,CK-MB、HBDH与感染程度呈正相关(r=0.518,0.527,P<0.01)。结论:联合监测CK-MB和HBDH有助于判断呼吸道感染患儿的病情严重程度。

Objective： To explore the variation and clinical significance of serum CK-MB and HBDH in children with respiratory infections.Methods：94 cases of children with respiratory infections（respiratory infections group） and 100 healthy children（control group） were studied,the serum CK-MB and HBDH levels were detected using immunosuppression methods.Results： The serum CK-MB and HBDH levels of the respiratory infections group were higher than the control group,compared difference was significant（P0.05）;the serum CK-MB and HBDH levels increased with increasing degrees of infections,the different degrees of infections were positively correlated with CK-MB and HBDH levels（r=0.518,0.527,P0.01）.Conclusion： Combined monitoring of serum CK-MB and HBDH of children with respiratory infections can help determine the extent of infections.