摘要
目的:为了了解药品不良反应发生的特点及规律,促进临床合理用药。方法:收集分析我院2005年1月~2010年6月各科室上报的药品不良反应(ADR)158例。结果:158例药品不良反应中,男75例,女83例。中老年人发生率最高,占52.53%。给药途径以静脉给药最多。主要不良反应症状为消化系统损害及皮肤损害。在不良反应轻重程度上,轻度者占76.8%,中度占22.4%,重度占0.8%。发生不良反应的患者转归较好,其中75.8%者治愈。24.2%的患者经采取有效措施后好转,无死亡病例。结论:加强药品不良反应监测、分析、总结、信息传播,为临床有效、安全、合理用药提供参考。
Objective: To understand the characteristics and rules of adverse drug reactions,and promote rational use of drug.Methods: Collected and analysized 158 cases adverse drug reactions(ADR) of our hospital from January 2005 to June 2010.Results: In 158 cases of adverse drug reactions,there were 75 cases men and 83 cases women.Highest incidence in the elderly,in the percent of 52.53 were the elderly.The most of the routes of administration were intravenous.The main symptoms of adverse drug reactions were damages to the digestive system and skin.On the severity of adverse reactions,in the percent of 76.8 were the mild and the percent of 22.4 were the moderate and the percent of 0.8 were the severe.The patients with adverse reactions have better outcomes,75.8% of them were cured,24.2% of patients improved by taking effective measures with no deaths.Conclusion: Strengthening the monitoring,analyze and summarize the information dissemination of adverse drug reactions to provide reference for clinically effective,safe and rational use of drugs.
出处
《中国医药导报》
CAS
2011年第5期108-109,共2页
China Medical Herald
关键词
药品不良反应
分析
合理用药
Adverse drug reactions
Analysis
Rational use drugs