肺部真菌感染的早期经验治疗

The Early Experiential treatment for fungal Infection of lung

目的:探讨肺部真菌感染发病的危险因素、病原学分布、临床特征、治疗及转归情况。方法:通过对我院2009年1月～2010年4月50例早期经验性治疗的肺部真菌感染患者临床资料进行回顾性分析。结果:大部分患者有基础疾病,以呼吸系统疾病为主,长期使用抗生素、糖皮质激素是该病的易患因素。病原菌以念珠菌为主,其次为曲霉菌。肺部真菌感染的早期经验性治疗可提高该病治愈率。结论:肺部真菌感染是多种疾病继发感染的重要原因,特异性少,病死率高,早期诊断及治疗尤为重要。

Objective：To explore the risk factors,pathogen distribution,clinical features,treatment and prognosis of fungal infection of lung.Methods：50 cases with fungal infection of lung from January 2009 to April 2010 in my hospital who were early experientially treated were retrospectively analyzed.Results：Most of them had predisposing diseases in which COPD,bronchiectasis,tumor and diabetes were major.Long-term use of antibiotics and corticosteroids and hypoalbuminemia were significant risk factors.Candida was ranked as the first pathogen and aspergillus followed it.Early diagnosis and treatment could improve the healing rate of fungus infection of lung.Conclusion：Fungus infection of lung is the secondary infection in many diseases.The clinical features of fungal infection of lung is not specific and the morbidity of it is high.Early diagnosis and treatment are particularly important.