摘要
目的建立旋光法测定鞣柳硼三酸散中硼酸的含量。方法以低浓度明胶溶液提取制剂中硼酸,利用甘露醇结合硼酸形成具有旋光性复合物,并建立鞣柳硼三酸散中硼酸的含量测定方法。结果硼酸浓度在5～20 g.L-1的浓度范围内与旋光度线性关系良好(r=0.999 2),方法的平均回收率为99.98%,RSD为1.3%。结论旋光法测定鞣柳硼三酸散中硼酸的含量,操作简便、快速,结果准确,重现性好。
Aim To establish a polarimetric method for determining boric acid in tannic acid,salicylic acid and boric acid powder.Methods 1% glutin solution was used to extract the boric acid in tannic acid,salicylic acid and boric acid powder.The polarimetric compound was composed of mannitol and boric acid.Results Good linear relationship was shown between boric acid（within the range of 5～20 g·L-1） and optical rotation（r=0.999 2）.The average recovery was 99.98%,and RSD was 1.3%.Conclusion This method is simple,rapid,accurate with good reproducibility.
出处
《安徽医药》
CAS
2011年第2期166-167,共2页
Anhui Medical and Pharmaceutical Journal
关键词
鞣柳硼三酸散
硼酸
旋光法
tannic acid
salicylic acid and boric acid powder
boric acid
polarimetric method
