斑秃患者107例生存质量及影响因素调查

Life quality and its influence factors in 107 cases of alopecia areata

[目的]对斑秃患者的生活质量进行评价并探讨其影响因素。[方法]应用皮肤病生活质量指数(der-matology life quality Index,DLQI)和非特异性生活质量量表(the short form-36 health survey,SF-36)对107例斑秃患者和102例对照组的生活质量进行量化评估,并比较两种方法评价差异。[结果]斑秃组DLQI评分高于对照组,差异有统计学意义(P<0.05);SF-36评分斑秃组低于对照组,在活力、情感职能、社会功能三个方面差异有统计学意义(P<0.05);逐步回归分析结果显示,病程、脱发面积及复发情况进入回归方程有统计学意义(P<0.05),且与DLQI结果正相关,与SF-36结果负相关。[结论]斑秃对患者的生活质量造成负面影响,应积极治疗;DLQI量表和SF-36量表适用于斑秃患者生活质量的评价;病程越长,脱发面积越大,复发的患者DLQI越高、SF-36越低,即生活质量越差。

[Objective] To evaluate the quality of life in cases of alopecia areata and explore its influence factors. [Methods] Questionnaires were done in 107 cases of alopecia areata and 102 control cases with DLQI and SF-36. [Results] The DLQI scores in alopecia group were higher than those in the control group（P0.05）.The SF-36 scores in alopecia group were lower than those in the control group（P0.05）.Vitality,social function and emotional function may influence the result.Stepwise regression analysis showed duration of disease,hair loss area and the recurrence was statistically significant in the regression equation,with positive correlation with DLQI and negative correlation with SF-36. [Conclusion] Alopecia areata reduces the quality of life.Early treatments are essential for relieving patients from psychologically devastating effects.The DLQI and SF-36 are good evaluation methods for evaluation of quality of life in cases of alopecia areata..As the duration is longer,the area of hair loss becomes larger,DLQI in recurrent cases is higher and SF-36 lower,that is,the quality of life is worse.