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Mdm-2、p16在大肠癌中的研究进展 被引量:6

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摘要 近年来,对肿瘤与细胞周期深入研究,越来越清晰地认识到肿瘤是一类细胞周期疾病和细胞周期调控机制在肿瘤的侵袭、转移的过程中起着重要作用。细胞周期中最主要的调控点在G1~S转折和G2~M转折的DNA损伤关卡:①G1~S期关卡监控DNA是否损伤;②G2~M处的关卡监控DNA是否损伤及DNA是否正确、完全的复制,其分别控制DNA复制和细胞的有丝分裂。
作者 付昌征 钱军
出处 《中华全科医学》 2011年第3期441-442,共2页 Chinese Journal of General Practice
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