摘要
目的探索5-羟色胺(5-HT)在青少年网络成瘾发生中的作用,为心理疏导、行为干预和药物治疗提供依据。方法应用高效液相色谱法,测定33例网络成瘾患者青少年和44例正常对照的血小板5-HT含量;采用抑郁自评量表(SDS)、焦虑自评量表(SAS),测评情绪状态。应用SPSS 14.0进行t检验和相关分析。结果网络成瘾组血小板5-HT水平低于正常对照组,差异有统计学意义(t=-2.135,P<0.05);网络成瘾组抑郁评分高于对照组,差异有统计学意义(t=3.310,P<0.01);网络成瘾组焦虑评分高于对照组,差异有统计学意义(t=3.110,P<0.01)。相关分析显示,血小板5-HT水平与网络成瘾、抑郁、焦虑程度均呈负相关(P值均<0.05)。结论网络成瘾发病可能与神经元功能失调有关。
Objective To explore the role of serotonin { 5 - HT） in interact addiction disorder （ lAD ） , and to provide evidence for the behavioral intervention and medical treatment. Methods Thirty-three adolescents with lAD and 44 normal ones as control were included in the study. Platclet serotonin level was determined with high performance liquid chromatography. Emotional status was investigated with Self-rating Depression Scale （SDS）and Self-rating Anxiety Scale （SAS）. A t-test and correlation analysis were used by SPSS 14.0. Results Platelet serotonin level of IAD was significantly lower than that of controls （ t = -2. 135 ,P 〈0.05 ）. SDS and SAS scores of IAD group were significantly higher than that of control group （ P 〈0.05 ）. Correlation analysis showed platelet serotonin level was related with the degree of IAD, SDS and SAS（ P 〈0.05 ）. Conditsion lAD is perhaps related to neurons＂ maladjustment.
出处
《中国学校卫生》
CAS
北大核心
2011年第2期190-191,共2页
Chinese Journal of School Health
基金
国家"十一五"科技支撑计划项目(2007BAI17B03)
关键词
因特网
行为
成瘾
血小板
血清素
青少年
Internet
Behavior, addictive
Blood platelets
Serotonin
Adolescent
