放射性核素^(89)Sr治疗前列腺癌骨转移

^(89)Sr Treatment for Bone Metastases in Patients with Prostatic Cancer

目的:探讨利用^(89)Sr治疗前列腺癌骨转移的临床效果。方法:选取47例前列腺癌骨转移病人,采用静脉滴注^(89)Sr的方法进行治疗,每6个月注射一次。结果:^(89)Sr治疗前列腺癌骨转移患者不但可使骨转移疼痛缓解(91.7%),而且对骨转移肿瘤灶有显著的治疗作用(85.11%)。结论:放射性核素治疗方法简单,副作用较小,治疗效果较好,具有很强的临床实用性。

Objective To study the effects of 89Sr treatment for bone metastases in patients with prostatic cancer. Methods Forty-seven patients with bone metastases from prostatic cancer received intravenous Sgsr （148MBq） every 6 months for more than three times （the longest ones even over ten times）. Results The effects of Sgsr treatment on bone metastases from prostate cancer were pain palliation complete remission ＋ partial remission, CR ＋ PR （91.7%） and tumor reduction CR ＋ PR （85.11%）. Conclusion Radionuchde 89Sr therapy for prostate cancer patients with bone metastases is quite effective with much improvement of quality of life.