尿白蛋白肌酐比与高血压患者危险因素的探讨

To investigate urinary albumin creatinine ratio(UACR) and rick factors in hypertension patients

目的研究尿白蛋白肌酐比(urinary albumin creatinine ratio,UACR)与高血压患者危险度的关系。方法对入选的174例尿白蛋白/肌酐异常的高血压患者进行Logistic回归分析;并按心血管疾病的危险因素、靶器官损害和相关的临床情况将高血压患者分为四组:低危组(n=14),中危组(n=26),高危组(n=21),极高危组(n=113),所有患者均检测血脂、血压,UACR。结果 Logistic回归分析显示脂肪肝和收缩压与UACR异常的高血压患者具有关联性。在危险度组分析中TCHO、TG、HDL和LDL在四组间无差别。UACR在低危组与高危组及极高危组间有差异(P<0.05)。结论高血压患者的危险度与尿白蛋白排出量相关联。

Objective To demonstrate the relationship between urinary albumin creatinine ratio（UACR） and risk levels in hypertension patients.Methods 174 selected cases of hypertension with abnormal urinary albumin/creatinine were studied and subjected to Logistic regression analysis,with consideration of risk factors in cardiovascular conditions,damage to target organs and relevant clinical situations.These cases were classified into：low risk（n=14）,average risk（n=26）,high risk（n=21） and extremely high risk（n=113） groups.Lipid level,blood pressure and UACR of all patients involved were analyzed.Results The analysis revealed a connection between abnormal UACR and fatty liver as well as level of systolic pressure.In analysis of risk levels,no specific value of TCHO,TG,HDL and LDL was discovered among groups.Regarding UACR,a significant difference（P0.05） was noted between the low risk and high risk as well as the extremely high risk group.Conclusion The amount of urinary albumin discharged in hypertension patients was associated with severity and risk level of the condition.