过敏性紫癜患儿食物不耐受检测及其意义

Determination of serum specific IgG of intolerance food measurement in anaphylactoid purpura

目的探讨过敏性紫癜患儿食物不耐受血清特异性IgG水平对其病因诊断及饮食治疗的意义。方法用食物不耐受IgG体外检测试剂盒检测30例过敏性紫癜患儿和20例健康对照儿童的血清特异性IgG水平。结果实验组30例过敏性紫癜患者的血清总IgG阳性率为76.67%,其中对1种食物不耐受为3例,对2种以上食物不耐受者为20例。健康对照组20例血清总IgG阳性率为25%,对1种食物不耐受为2例,对2种以上食物不耐受者为3例,常见的引起不耐受的食物依次为牛奶、虾、鸡蛋清和鸡蛋黄、蟹、大豆、鳕鱼、大米、小麦、猪肉、牛肉等,实验组饮食上经避免不耐受食物及抗过敏治疗疗程缩短,疗效优于对照组。结论血清特异性IgG水平检测对过敏性紫癜的病因诊断有参考意义,对患儿饮食治疗及营养状态的改善具有重要的指导意义。

Objective To analyse the significance of diagnosing the pathogenies for the serum specific IgG level and the food therapy in the anaphylactoid purpura patients.Methods Using the IgG food intolerance external assay,the specific IgG level was detected in the serum of 30 cases of anaphylactoid purpura.Results Total positive rate of serum IgG in the ingestive group was 76.67%,in which 3 cases were sensitive to 1 kind of ingestants and 20 cases over 2 kinds of ingestants.In the control group,total positive rate of serum IgG was 25%,in which 2 cases were sensitive to 1 kind of ingestants and 3 cases over 2 kinds of ingestants.The common food inducing intolerance were milk,shrimps,egg white and yolk,cab,soybeans,fish,rice,wheat,pork,beef in turn.Avoiding the intolerance food and therapy with anti-allergen drugs can lessen the cause of the disease,the effect was better than the control group.Conclusion：The serum specific IgG level has important reference significance for diagnosing the pathogenies in the anaphylactoid purpura and has instuction role to the food therapy,and can improve the condition of anaphylactoid purpura patients＇nurtrition.