食管胃静脉曲张出血的治疗进展

Progress in Management of Esophogastric Variceal Bleeding

食管胃静脉曲张出血(EGVB)是肝硬化患者常见的并发症,病情凶险,出血量大,病死率高。其治疗目标是预防EGVB首次出血、控制活动性出血和预防再出血,以降低病死率。治疗方法包括药物治疗、内镜下静脉曲张套扎、硬化治疗、组织粘合剂注射治疗、介入治疗、联合治疗以及外科手术治疗。根据内镜下的不同情况以及肝功能的分级等采取不同的治疗方法。现就EGVB治疗方法的一些新进展予以综述。

Esophagogastric variceal bleeding（EGVB）is a common complication in cirrhotic patients,with a life-threatening severity,massive bleeding volume,and a high mortality.The therapeutic goal is to prevent the initial gastroesophageal variceal bleeding,control active bleeding and recurrent bleeding,in aiming to lower down the mortality.The therapeutic modalities include medication,endoscopic variceal ligation,endoscopic variceal sclerotherapy,tissue adhesive therapy,interventional therapy,combination treatment,and surgical treatment.The choice of therapeutic regimens depends on the endoscopic outcomes and liver function classification.This article reviews the recent progress in EGVB treatment.