卵泡穿刺术在治疗多囊卵巢综合征不孕症中的应用被引量：1

Treatment of polycystic ovary syndrome complicated with infertility by ultrasound-guided follicle puncture

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摘要目的观察B超引导下经阴道卵泡穿刺治疗多囊卵巢综合征(PCOS)合并不孕症患者的临床效果。方法将83例合并有多囊卵巢综合征但输卵管通畅的不孕患者随机分成A、B两组。给予药物治疗后,A组(n=42)在阴道B超超声介导下行成熟卵泡穿刺协助排卵,并指导同房;B组(n=41)药物促排卵后指导同房。结果 A组患者临床妊娠率为40.48%,B组患者为21.95%;A、B组患者多胎妊娠率分别为9.52%和19.51%,卵巢过度刺激综合征(OHSS)发生率分别为16.67%和31.70%,两组比较均有显著差异(P<0.05)。结论 B超引导下经阴道卵泡穿刺术是PCOS合并不孕患者的一种有效的治疗方法。 Objective To investigate the clinical effect of transvaginal ultrasound-guided follicle puncture for patients with polycystic ovary syndrome（PCOS）complicated with infertility.Methods 83 cases of infertility complicated with PCOS were divided into two groups randomly.Group A patients were used transvaginal ultrasound-guided follicle puncture after ovulation stimulants,and natural fertilization;group B received ovulation stimulants and natura1 fertilization.Results The rate of pregnancy,multiprenancy and OHSS for group A and B 40.48% vs 21.95%,9.52% vs 19.51%,16.67% vs 31.70% respectively.There was significant difference between two group（P0.05）.Conclusion Transvaginal ultrasound-guided follicle puncture is an effective method for treating PCOS complicated with infertility.

作者刘新雄

机构地区钦州市妇幼保健院

出处《中外医学研究》 2011年第4期5-6,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH

关键词多囊卵巢综合征经阴道卵泡穿刺促排卵 Polycystic ovary syndrome Transvaginal follicle puncture Controlled ovarian

分类号 R711.75 [医药卫生—妇产科学]

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参考文献5

1Nader S.Ovulation induction in polycystic ovary syndrome.Minerva Gyinecol,2008,60(1):53-61.
2冯巧飞,刘宏,何援利,潘石蕾.胰岛素增敏剂联合达英-35治疗多囊卵巢综合征疗效观察[J].广东医学,2009,30(8):1171-1173. 被引量：23
3The Rotterdam ESHRE/ASRM-sponsored PCOS Consensus-Workshop Group.Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome(PCOS).Fertil Steril,2004,81(1):19-25.
4朱桂金,徐蓓.PCOS患者诱发排卵的方案[J].实用妇产科杂志,2007,23(3):131-134. 被引量：36
5陈冬云.经阴道小卵泡抽吸术治疗多囊卵巢综合征的临床观察[J].中国医学创新,2008,5(32):32-33. 被引量：2

二级参考文献14

1张会娟,李道明,欧阳军.二甲双胍联合吡格列酮治疗多囊卵巢综合征的疗效及安全性[J].中华内科杂志,2005,44(11):856-857. 被引量：9
2MATTHEWS D R, HOSKER J P, RUDENSKI A S, Homeostasis model assessment: insulin resistance and betacell function from fasting plasma glucose and insulin concentrations in man [ J]. Diabetologia, 1985, 28(7): 412-419.
3AZZIZ R. Polyeystic ovary syndrome, insulin resistance, and molecular defects of insulin signaling [ J ]. Clin Endocfinol Metab, 2002, 87(9) : 4 085 -4 087.
4JEFREY E P, SALTIEL A, Signaling pathways in insulin action: molecular targets on insulin resistance[ J]. Clin Invest, 2000, 106 (2) : 165 -169.
5CAGNACCI A, PAOLETTI A M, RENZI A. Glucose metabolism and insulin resistance in women with polycystic ovary syndrome during therapy with oral contraceptives containing cyproteroue acetate or desogestrel [ J ]. Clin Endocfinol Metab, 2003, 88 ( 8 ) : 3 621 -6 325.
6SAHIN I, SERTER R, KARAKURT F, Metformin versus flutamide in the treatment of metabolic consequences of non -obese young women with polycystic ovary syndrome: a randomized prospective study [ J ]. Gynecol Endocrinol, 2004, 19(3): 115-124.
7Nardo LG.Management of anovulatory infertility associated with polycystic ovary syndrome:tamoxifen citrate an effective alternative compound to clomiphene citrate[J].Gynecol Endocrinol,2004,19(5):235-238.
8Beck JI,Boothroyd C,Proctor M,et al.Oral anti-oestrogens and medical adjuncts for subfertility associated with anovulation[J].Cochrane Database Syst Rev,2005,Jan 25 (1):CD002249.
9AL-Fadhli R,Sylvestre C,Buckett W,et al.A randomized trialof superovulation with two different doses of letrozole[J].Fertil Steril,2006,85 (1):161-164.
10Holzer H,Casper R,Tulandi T.A new era in ovulation induction[J].Fertil Steril,2006,85 (2):277-284.