摘要
目的探讨老年脑胶质瘤患者应用化疗药物后的毒副反应。方法将146例应用化疗药物的脑胶质瘤患者根据年龄分为老年组70例（≥60岁）和中青年组76例（〈60岁），然后进行组间比较，所有患者均采用替尼泊甙（VM-26）＋司莫司汀（Me-CCNU）联合化疗方案。结果老年组的骨髓抑制现象和呕吐反应（25．0％和23．9％）并不高于中青年组（23．8％和24．2％）（P〉0．05）。结论老年脑胶质瘤患者实施化疗是安全的，毒副反应并没有增加。
Objective To explore the toxic reaction of chemotherapy for older patients with brain glioma. Methods 146 patients with brain glioma were divided into two groups： age ≥60 years group and age 〈60 years group. 70 patients each group. All the patients were treated with VM-26 and Me-CCNU. The side effects in the two groups were compared. Results There were no differences in the myelotoxicity and the vomit between the two groups （ 25.0 % vs 23.8 %; 23.9 % vs 24.2% ）. Conclusions The chemotherapy in the elderly patients with brain glioma is safe and has little side effect.
出处
《老年医学与保健》
CAS
2011年第1期49-51,共3页
Geriatrics & Health Care
关键词
老年人
脑胶质瘤
化疗
毒副反应
Elderly
Brain glioma
Chemotherapy
Side effect
